Potassium Citrate vs Potassium Bicarbonate which is more bioavailable

 

Potassium Citrate vs Potassium Bicarbonate: Bioavailability and Blood Pressure

When comparing the bioavailability and effects on blood pressure of potassium citrate and potassium bicarbonate, it is important to consider the available information. Let's examine the search results to provide a comprehensive answer.According to the search results:

1. Potassium Citrate:
   • Potassium citrate is commonly used to treat or prevent certain types of kidney stones 
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   • It is typically taken orally 2 to 3 times daily with food.
   • Potassium citrate is equivalent to the brand-name medication Urocit-K 
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   • There are potential side effects of potassium citrate, including hyperkalemia and stomach bleeding 
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   • Potassium citrate comes in an extended-release (ER) tablet form 
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2. Potassium Bicarbonate:
   • One study suggested that adding potassium bicarbonate to a high-potassium, low-salt diet may reduce blood pressure and benefit cardiovascular health 
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   • Potassium bicarbonate supplementation showed significant improvement in endothelial function, which is important for blood flow to and from the heart 
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   • Multiple studies support the role of potassium bicarbonate in improving heart health 
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   • Potassium bicarbonate may also help with bone strength and density by reducing calcium loss 
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3. Blood Pressure:
   • Randomized trials have shown that increasing potassium intake, including through supplementation, can lower blood pressure 
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   • The DASH study demonstrated that an increase in potassium consumption from fruits and vegetables, along with an increase in 24-hour urinary potassium, led to a decline in blood pressure 
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   • A study on predominantly normotensive volunteers explored the effects of potassium chloride and potassium citrate on blood pressure and found that both salts had a similar effect 
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   • The alkalosis induced by potassium citrate or sodium bicarbonate may reduce renal dopamine production, but it is unclear how this change in urinary dopamine would influence the effect of potassium on blood pressure 
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Based on the available information, both potassium citrate and potassium bicarbonate have potential benefits for blood pressure and cardiovascular health. Potassium bicarbonate, in particular, has shown positive effects on endothelial function and may help with bone strength and density. However, it is important to note that the effects of potassium supplementation on blood pressure may vary depending on individual factors and overall dietary patterns.It is always recommended
to consult with a healthcare provider or pharmacist to determine the most appropriate potassium supplement for individual needs and to discuss potential interactions or side effects.Note: The information provided is based on the search results and should not replace professional medical advice.
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